Holt-oram

Inheritance

 * Autosomal Dominant

Molecular Etiology

 * TBX5

Associated Birth Defects

 * Cardiac Defects
 * Atrial Septal Defect

Musculoskeletal

 * Limb Abnormalities
 * Absent Pectoralis Major Muscle
 * Absent, bifid, or triphalangeal thumb
 * carpal bone anomalies
 * Shortened upper limbs